Center fund research study trial

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases. Learn How to Help. Get canine health news: Please leave this field empty. Participate in Research Canine health researchers throughout the country are looking for dogs to help them better understand disease. DNA samples from any purebred dog may be submitted at any time. Researchers may then access these samples to be included in their canine health studies.

Learn more at the CHIC website. CHF-funded Grant: CHF-funded Grant: A. Ages with the age of onset greater than Contact : Anita Seto, PhD, , info expansionrx. Location : Online Survey Sponsor :. Conditions : Expectant couple pregnant woman between 9 and 34 weeks of gestation and her spouse at risk of transmitting a triplet-repeat related genetic disease including Myotonic Dystrophy type 1 Location :.

Clinical trials are studies conducted using human participants to assess the safety and activity of new therapies in development. Clinical trials produce a lot of interest and excitement. This trial is an important first step, and all of us are interested in having it go well. Even if this medication does not work, we will learn as much as possible to guide the development of newer and better treatments in the future.

Clinical trials can be categorized into distinct phases depending upon the stage of clinical development of the drug. Phase II and III studies are larger, longer studies in affected individuals that continue to evaluate the safety of the drug as well as the activity and effectiveness of the drug prior to requesting regulatory agencies for marketing approval.

Phase IV studies are studies designed to provide additional information about a drug that has been approved for marketing and is already available to qualified patients. A placebo is an inactive drug administered to some of the patients the placebo arm or control group in a trial. This control group is essential as it provides a basis for comparison and for assessing the effects and efficacy of trial drugs.

Well-controlled clinical studies, which often include placebo arms or groups, are necessary to establish the risk and benefit profile of the compound, as well as toevaluate the safety and tolerability of trial drugs. A blinded clinical trial means you, your study doctor, and the study staff will not know if you have been given active drug or placebo. This helps to ensure that bias doesn't distort the conduct of the trial or the interpretation of the results.

We understand the community is eager to hear about results and the experiences of those participating, but sharing this information publicly can have a significant impact on the study, such as bias the results of a double-blind trial, potentially unblind the trial altogether, or even render the study inconclusive causing the trial to fail whether the treatment was effective or not.

We know the community is anxious to get to effective treatments. We all have a role to play in making sure that we are supporting these clinical trial efforts. For more information on discussing clinical trials publicly, please click here. NCCIH research priorities for most natural products are at the exploratory end of the research and development continuum. At this stage of research, NCCIH has broad interest in studying the biological activities of natural products, including studies in preclinical models for a wide variety of potential clinical indications.

The development of new resources e. One of the foundational hypotheses of herbal medicine is that complex products contain a combination of compounds that are more effective and less toxic than any isolated constituent. However, to completely understand the activity of a complex product, it is necessary to identify the individual chemicals responsible for that activity and how they interact with each other in preclinical model systems.

Therefore, NCCIH has interest in studying the isolated compounds as well as the complex mixtures from which they originate. This can also include discovery and characterization of new natural products. Targeted development and large clinical trials will be warranted only when basic and translational research allows rigorous testing of evidence-based hypotheses.

Importantly, NCCIH believes that maximally informative clinical efficacy studies of natural products should be based on a solid foundation of mechanistic research. Therefore, late-stage clinical efficacy research will necessarily be limited to those natural products with a substantial body of evidence in preclinical models. NCCIH is committed to the rigorous scientific investigation of natural products used in complementary and integrative health practices.

Sufficient product information must be included in the application to allow the peer reviewers to evaluate the significance, feasibility, and scientific strength of the project. Investigators must demonstrate that their investigative team has the appropriate product and analytical expertise to select the test and placebo agents for study and to ensure product integrity.

For example, botanists trained in taxonomy may be required to identify voucher specimens accurately. Experts in natural products chemistry, microbiology, food science, botany, pharmacognosy, analytical chemistry, etc. The Center works to identify and fund research in two priority areas outlined in the HEAL scientific research plan:.

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